gigsMO, there isn't a Skype App in the store. Your only option would be to root your Nook and get Skype from Android Market.
Not a NOOK solution, but do you have a smartphone that can run Skype? That's what I often use on the road as you describe.
If you want to use Skype but don't want to root you can always boot off a SD card witch can be made for free or bought pre-made from N2A or Android for Nook.
If you want to make a CM7 SD yourself here is a guide here.
Hope this helps