I don't think so.
I initially made an error in my email address on my Nookcolor and realize it might be the reason I am unable to access my BN library account. (The BN account email is correct) Is there anyway to correct the email on my Nookcolor without reregistering and losing all the books? They will be lost because they do not appear in my BN library online.
By unregistering and re-registering you will NOT lose any of your content from B&N. You may have to re-download it, but your B&N library is "permanent" and the books and stuff you are entitled to here, will still be available.
Now...if you've bought stuff using a different account (what you registered the nook with) then yes, you'll lose that content because a NC can only be associated with ONE account.
Meaning when you registered your NC you created a new account with yoiur mis-spelled email.
As to changing the email on your mis-spelled account.....I doubt it, but I'd contact Customer Service (optin 2 Digital support) for an answer.